At least 33 people were injured in a strike on a building in northern Israel, the Ynet news portal reported.
Air raid sirens were heard before the explosion.
The Israel Defense Forces' Home Front Command previously announced that it had detected missiles fired from Iran towards Israel.
Iran confirmed that it had fired a new wave of missiles at Israel in a statement on the Islamic Republic's state television.
The Islamic Revolutionary Guard Corps has used missiles with a 2-ton warhead as part of the final phase of its operation against Israel and the United States, according to a statement by the military operator on the Islamic Republic's state television.
Iran has advised Arab countries not to accommodate American citizens in their hotels and their populations to avoid areas where Americans gather or congregate, so as not to expose themselves to the risk of surprise attacks from Iran, the Islamic Revolutionary Guard Corps' intelligence service said in a statement.
Air defense systems Saudi Arabia's defense forces intercepted 28 Iranian drones overnight, the kingdom's Defense Ministry announced.
China opposes attacks on energy and social facilities during armed conflicts, China's special envoy for the Middle East, Zhai Jun, said during a meeting in Manama with Bahraini Foreign Minister Abdel Latif bin Rashid al-Zayani.
Colombia, along with Mexico, Brazil and other countries, will sign a communiqué calling for a ceasefire and the start of peace talks in the Middle East, Colombian President Gustavo Petro announced.