The main hospital in southern Israel was hit early this morning in a massive Iranian missile attack, DPA reported.
Several Israeli media outlets reported that a missile fired from Iran hit the "Soroka" hospital in the desert city of Beersheba.
Iranian airstrikes have also been carried out on other locations in Israel, including in the Tel Aviv area.
At least 25 people have been injured across the country, at least three of them seriously.
The Israeli military said on social media that rescue teams were working at several locations in Israel that had been hit by Iranian missiles.
Earlier today, the military said it had struck targets in Iran, including in the capital Tehran. The Israeli military said Iran had fired several missiles at Israel in the morning.